Exchange transfusion for severe falciparum malaria in pregnancy.

Exchange transfusion as an adjunct therapy in severe Plasmodium falciparum malaria: a meta-analysis.

The efficacy of exchange transfusion as an adjunct treatment for severe falciparum malaria is controversial. No sufficiently powered, randomized, controlled study has been reported. We analyzed 8 studies that compared survival rates associated with adjunct exchange transfusion with those associated with antimalarial chemotherapy alone. Exchange transfusion was not associated with a higher survi...

Exchange transfusion with red blood cells preserved in adenine clears a child of severe falciparum malaria.

Falciparum malaria may be associated with significant morbidity and mortality. The degree of mortality and morbidity usually corresponds to the degree of parasitemia. Quinine and other antimalarial drugs are relatively slow acting and not always effective owing to the presence of drug resistance falciparum. Rapid reduction of the number of circulating parasites may be required. Exchange transfu...

Role of exchange transfusion in patients with severe Falciparum malaria: report of six cases.

Exchange transfusion for severe malaria: evidence base and literature review.

BACKGROUND Exchange transfusion (ET) has biologic plausibility as an adjunct to antimalarial drugs in treating severe malaria and has been used for decades despite limited evidence of its efficacy in improving survival. We examined the efficacy of ET as an adjunct treatment for severe malaria using US surveillance data and reviewed the literature to update recommendations. METHODS Patients wi...

Severe neonatal hyperbilirubinemia leading to exchange transfusion

  Background :Severe neonatal hyperbilirubinemia is associated with significant morbidity and mortality. This study was conducted to investigate the causes of severe hyperbilirubinemia leading to Exchange Transfusion (ET) from March 2009 to March 2011 in Bahrami children hospital, Tehran, Iran in order to establish guidelines to prevent profound jaundice & ET.   Methods : 94 neonates underwent ...